Health

The Xlerator hand dryer.Have you noticed how hand dryers in public bathrooms have gotten more high tech lately? Super concentrated bursts of dry air that promise to work quickly and actually are noticeably faster than their predecessors? You can thank three MITers for that: Sol Aisenberg PhD ’57; George Freedman ’43; and Richard Pavelle, who was on the research staffs at MIT’s Laboratory for Computer Science and Lincoln Lab.

They are three of the four scientists at Invent Resources, Inc. (IRI), a company they cofounded during their retirements to create inventions on demand. Together, the four IRI scientists have expertise in just about every scientific discipline that would be useful for invention. Their “fields of competency” list includes cryogenics, general relativity, energy conversion, plasma physics, advanced materials, novel chemical processes, and medical technology, among scores more.

Before retiring, Aisenberg led the high-tech divisions of several Fortune 500 companies and pioneered ion-assisted deposition and demonstration of hydrogen-free artificial diamond film materials.

Freedman founded and was director of Raytheon’s New Products Center. One team he led produced the world’s first samarium cobalt magnets that were stronger than those that could be measured at the National Magnet Lab at MIT and were later used in Patriot missiles and tools used in space.

Pavelle patented the credit card calculator, golf-club faces that expanded the sweet spot and are now industry standard, and an electrochemical process that reduces charging times for batteries.

And then they took on commercial hand dryers, discovering that the previous models wasted 90 percent of the energy going into them. In this case, IRI had already unsuccessfully pitched their idea for a faster hand dryer to industry leader World Dryer. But Excel Dryer of East Longmeadow, Mass., a small family owned company, hired them to create a product people would actually want to use.

IRI scientists were  shooting for 10 seconds of drying time—down from 30–40 seconds, but after three-and-a-half years of work got it down to 12, which is now the standard. Excel owner Denis Gagnon was so certain the engineering team at IRI had created a revolutionary product that he risked his life savings: he borrowed against his home and life insurance, drained his bank accounts, and took loans from friends and relatives.

The resulting product was the Xlerator, the first revamped hand dryer to hit the market. Others have since followed, like the Dyson Airblade that you stick your arms into.

According to an interview with NPR, Excel’s sales have risen more than 10 percent every year for the past decade. And there’s room for growth. Data suggest that there are 25 million public bathrooms nationwide not using automatic hand dryers, even though a basic-model Xlerator costs $400, offers 95 percent cost savings over paper towels, and has a significantly smaller carbon footprint.

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This is the final post in a series from two MIT students—Shawn Wen ’13 and Taylor Yates MBA ’14—involved in the 2013 Student/Alumni Externship Program, which connects current students with alumni in workplaces worldwide during MIT’s Independent Activities Period. These bloggers reported on what they learned and how the experience informed their career journeys. Alumni, learn how to get involved as a sponsor. Read the other posts in this series.

Guest Blogger: Shawn Wen ’13
Extern sponsor: Jon Glaudemans ’80
Company: Ascension Health, Washington, DC
Externship: health policy analysis

Shawn (far left) and her older brother (right) enjoying dinner with Becky Donnellan ’72 (back left) and her family.

Clockwise, from front left: Shawn Wen ’13, Meaghan Karch (daughter of Shawn’s host, Becky Donnellan), Becky Donnellan ’72, Nate Karch (Becky’s husband), and Jason Wen (Shawn’s brother).

As I wrap up my final week at Ascension Health (AH), I am amazed at what I have had the opportunity to do this month. In this past week alone, I have attended congressional hearings; participated in an Alliance for Health Reform briefing on strategies for bending the health-cost curve; researched and prepared data charts on Medicaid Expansion for the CEO of AH; and learned about new, effective practices for reducing shoulder dystocia, a high-trauma birth event, from AH’s director of clinical excellence. I also have been invited to the David Winston Health Policy Gala to cap off my final night in Washington, DC!

What I have come to appreciate is the strength of the MIT connection. It’s something that has been well articulated by others before, but it hadn’t resonated with me so strongly until this externship experience. Becky Donnellan ’72 generously opened up her home and family to me, and my sponsor, Jon, despite traveling extensively, spent the few days he was in our DC office giving me insights on how to lead effectively, make others believe in your vision, and connect with others in professional and personal domains.

Amazingly, everyone I have met has taken a personal interest in helping me, an undergrad, despite their high-profile careers and busy lives. When prompted about my passions, I shared my ongoing work on a low-cost typhoid diagnostic system targeting resources-limited healthcare settings in developing countries, and immediately Jon and Becky both started lining up connections for me. The support was certainly unexpected, and it amazes me how they are personally and genuinely invested in me simply because we share a common alma mater. I doubt this exists at any other institution. Their desire to see me succeed and my desire to make them proud are powerfully motivating. I know I will stay in touch with them in the future.

In short, the Alumni Association’s Student/Alumni Externship Program is one of the most valuable and rewarding opportunities I’ve had at MIT—everyone should take advantage of it. Working at AH helped me build a critical understanding of barriers to the delivery and consumption of healthcare, which I know I will draw upon as a future physician. More importantly, interacting with Becky and Jon opened me up to a whole network of amazing people and helped me appreciate and recognize the type of mentor and person I aspire to become. I couldn’t have planned a more rewarding fourth and final IAP and am so wonderfully grateful to have had this opportunity.

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This is part of a series of posts from two MIT students—Shawn Wen ’13 and Taylor Yates MBA ’14—involved in the 2013 Student/Alumni Externship Program, which connects current students with alumni in workplaces worldwide during MIT’s Independent Activities Period. These bloggers will report on what they learn and how the experience informs their career journeys. Alumni, learn how to get involved as a sponsor. Read the other posts in this series.

Guest Blogger: Shawn Wen ’13
Extern sponsor: Jon Glaudemans ’80
Company: Ascension Health, Washington, DC
Externship: health policy analysis

Shawn at a Congressional hearing.

Shawn at a Congressional hearing.

This past Sunday, a day before President Obama’s Inauguration, I visited Mount Vernon Gardens and Estate. The property itself was beautiful, but perhaps the most poignant part about being at the former home of George and Martha Washington was being reminded of one of our first President’s greatest marks of leadership: his firm belief in the peaceful transfer of power and its shaping influence on how the US political system operates today.

As I watched the Inauguration on Monday among a mass of about 800,000 people packed onto the National Mall, I couldn’t help but feel lucky and moved to be a part of history. In 2009, President Obama made history by becoming the first African American President of the United States. This Monday marked a different kind of history. The nation faces extremely challenging issues, but like President Washington, we must find sound judgment despite being in uniquely challenging circumstances without any guiding precedence.

Scenes from the Inauguration crowd.

The view from the crowd at the Inauguration earlier this week.

A day after the Inauguration, the 113th Congress wasted no time in beginning hearings. I attended hearings at the Energy and Commerce and the Ways and Means Committees. Successes at the Energy and Commerce Committee, which included markup of pending legislation (including the Veteran Emergency Medical Technician Support Act and National Pediatric Research Network Act of 2013), were mixed with heated discussions about the debt ceiling at the Ways and Means Committee. Sloan Professor Simon Johnson PhD ’89, who gave testimony at the Ways and Means hearing, warned that failure to increase the debt ceiling would seriously and permanently undermine our standing in credit markets, increase interest rates, and worsen the budget deficit, which would have detrimental effects in the global economy.

What I am coming to appreciate about policy and governance is the interconnectedness of issues and the resulting challenges of finding comprehensive solutions. In the three hours of the hearing, no clear action steps were laid out. If anything, a world of challenges and exceptions were raised. But perhaps that’s how policy works. Dialogue is laboriously slow but critically necessary to allow all stakeholders to be heard, every viewpoint to be considered, and the most well-informed policy decisions to be made.

Scenes from the Inauguration crowd.

Scenes from the Inauguration crowd.

At the Committee on Energy and Commerce.

At the Committee on Energy and Commerce.

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This is part of a series of posts from two MIT students—Shawn Wen ’13 and Taylor Yates MBA ’14—involved in the 2013 Student/Alumni Externship Program, which connects current students with alumni in workplaces worldwide during MIT’s Independent Activities Period. These bloggers will report on what they learn and how the experience informs their career journeys. Alumni, learn how to get involved as a sponsor.

Guest Blogger: Shawn Wen ’13
Extern sponsor: Jon Glaudemans ’80
Company: Ascension Health, Washington, DC
Externship title: health policy analysis

Preparations for Inauguration Day at the Capitol Building.

Preparations for Inauguration Day at the Capitol Building.

Ascension Health (AH) is one of the largest health systems in the US, operating a network of over 400 hospitals and medical centers across the country, and I am lucky to call AH’s policy and advocacy office in Washington, DC, my home base this IAP. In just my first week, I have been warmly welcomed by a tight-knit office community and have been fully immersed in the excitingly fast-paced world of health policy. Some days, I am in the office in downtown DC, researching and preparing reports on various topics, such as mental health services to be included in the Affordable Care Act’s Essential Health Benefits package and implications of the recent changes in Medicare coverage for skilled nursing and therapy services for chronically ill beneficiaries.

Other days, I am tagging along with AH’s senior VP of policy, and I find myself in boardrooms in the company of some of the most influential thought leaders in health care as they engage in earnest discussions about the key driving forces in the health industry; threats of the upcoming budget talks on Medicaid reimbursement rates; and the necessity of moving away from a fee-for-service reimbursement system, which rewards high quantity of services, to shared savings, which rewards high-quality and coordinated care. Every day, I aim to develop more clarity on the world of complex challenges that bar cost-effective delivery of health care in the United States.

Next time, I’ll cover my thus-far fantastic experience living with an MIT alum and Inauguration Day.

About Shawn Wen ’13
I am a premed senior studying brain and cognitive sciences. The most interesting experience I’ve had at MIT has been working on implementing an electricity-free typhoid diagnostic system in resources-limited health-care settings in rural Nepal as an MIT International Development Initiative Technology Dissemination Fellow. Before beginning medical school, I plan on spending a gap year in Nepal channeling MIT’s fundamental principles of innovation and entrepreneurship into my personal engagement with global health and public service. I’m excited to explore yet another side of health-care delivery this IAP.

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Cheers (Click for video.)

One Friday evening last November, Media Lab research assistant Dhairya Dand attended a party. The next morning he awoke in a hospital—the result of too much alcohol the night before.

Shaken by the incident, Dand took a unique approach to make sure that incident would not happen again. The result: Cheers, pseudo-ice cubes that can calculate how fast and how much alcohol one is drinking.

A video created by Dand tells his story and shows Cheers in action. On the first drink, the cubes blink green. On the second, they blink yellow, which indicates drinking too much or too fast. If the drinking continues, the cubes flash red, signaling the drinker to stop. If the drinker continues past red, a custom text message can be sent to a friend alerting them of the situation.

The LED lights inside each cube.

The cubes are made from a coin cell battery, an ATtiny microcontroller, and IR transceiver, which are molded into a waterproof cube. They cost about $50 to produce and are currently not available for sale. Dand has no plans to patent his invention.

From ABCNews.com:

“I believe in open-source. My inventions are open to be hacked, developed and played around,” said Dand. “True innovation is like ideas with wings, once they take birth in a mind, nothing, not even the inventor, can stop them.”

Cheers is not Dand’s first unique research project. According to his website, his work specializes in superhuman interaction and his projects include Jellow, a communication device for children with cerebral palsy, and ThinkerToys, which converts discarded electronics into educational toys.

Cheers is not a substitute for responsible alcohol consumption and might require a few details (like the drink’s alcohol percentage) to be fully effective. But could these cubes serve as a deterrent to over-imbibing? Let us know in the comments below or on Facebook.

As Dand notes in his video, call 617-253-121 for any alcohol-related emergencies at MIT. In accordance with MIT’s practice for seeking help, MIT will treat the situation as a health and safety matter and not a disciplinary incident.

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You are invited to play an online game, Eyewire, and solve a major problem—filling the gap between the fast capture of brain synapse images and the slow mapping of their 3D connections manually. The game, open to all and learned online with simple instructions, will make you a citizen scientist as you advance MIT neuroscience research. And it’s fun!

Neuroscientist Sebastian Seung

Neuroscientist Sebastian Seung

Eyewire was created in Professor Sebastian Seung’s Computational Neuroscience Lab as a crowdsourcing solution to a time-consuming problem. Players earn points by correctly coloring in tendrils on detailed 3D images of retina synapses collected using serial block face scanning electron microscopy.

Seung believes understanding these connections between neurons—or connectomes—could reveal the roots of memory, personality, and mental disorders. He profiles his ideas in his recent book, Connectome: How the Brain’s Wiring Makes Us Who We Are, which he discussed in an April Faculty Forum Online interview. The Wall Street Journal’s Daniel Levitin called it “the best lay book on brain science I’ve ever read.”

Trace the synapses to win points, advance neuroscience.

Trace the synapses to win points, advance neuroscience.

How do you get started? Go to the Eyewire instructions page; take the tutorial, which explains what humans can do that computers can’t in the mapping process; and start to play (you can check your accuracy if you like).

Check out the blog for weekly player  stats and find out why scientists believe there are 100 billion neurons in the human brain.

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Guest blogger: Monica Kelly

Photo: Robbie's Photo Art/Flickr Creative Commons.

Photo: Robbie’s Photo Art/Flickr Creative Commons.

Anyone who encounters a North American porcupine would be wise to turn and run in the other direction, but researchers at MIT and Brigham and Women’s Hospital are getting up close and personal with these critters in the name of medical innovation. A study released in the December issue of the Proceedings of the National Academy of Sciences (PNAS) describes how these scientists believe the structure of the porcupine quill could be replicated to improve medical needles and adhesives.

Researchers discovered that the tips of porcupine quills are covered with numerous barbs that both facilitate the penetration of the skin and inhibit removal once inserted. A barbed quill requires approximately 50 percent less force than an un-barbed quill, and 60-70 percent less force than a standard medical needle to penetrate the skin’s surface. This discovery has pointed researchers on a path to creating a new medical needle that more efficiently and less painfully breaks the skin.

But needles are not the only medical tools that could be improved thanks to the results of this study. According to MIT Institute Professor Robert Langer ScD ’74, the senior author of the study, “With further research, biomaterials modeled on porcupine quills could provide a new class of adhesive materials.”

Adhesives such as medical superglue, sutures, and stitches are critical to the surgery recovery process, and stronger alternatives could lead to fewer post-op complications. Thus, these researchers are now using this new information about Mother Nature’s porcupine design to develop more effective, biodegradable medical adhesives that will safely disintegrate as the body heals.

Perhaps the porcupine is not the enemy after all.

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Yes, according School of Science Dean Marc Kastner. “MIT is the new Bell Labs,” he told an MIT audience just this morning. He says the Institute’s own researchers plus collaborations with nearby hospitals make MIT the hottest place to unravel the mysteries of diseases such as Alzheimer’s, autism, cancer, and psychiatric disorders.

Discovering disease mechanisms is key, says Mirganka Sur, head of a research center focusing on autism.

Discovering disease mechanisms is key to developing effective treatments, says Mirganka Sur, head of a research center focusing on autism.

Brain and nervous system diseases—from mental disorders, which impact 25% of the U.S. population, to Alzheimer’s, which claims 50% of Americans older than 85—have a huge personal and economic impact. Further, none of these brain-based diseases have a treatment solution that is based on a deep understanding of the mechanism of the disease—what goes wrong. In depression, for instance, medications only help some people and the impact can wane over time; in Alzheimer’s, no effective medications exist despite decades of research.

Kastner brought together colleagues from four research centers to make the case that MIT has the tools to tackle these problems—and there is reason for optimism.

Li-Huei Tsai, head of the Picower Institute for Learning and Memory, described the Obama administration’s call for a Moon shot-scale effort to understand and treat Alzheimer’s disease, currently the sixth largest cause of death in the US. More money is needed, though, to crack this disease, she says. Some MIT efforts include Manolis Kellis’s work using massive data crunching to understand the fundamental differences between a normal brain cell and one affected by Alzheimer’s. Kellis, the head of MIT’s Computational Biology Group, is a leader of the global consortium known as ENCODE, which stands for Encyclopedia of DNA Elements.

School of Science Dean Marc Kastner.

School of Science Dean Marc Kastner listens to researchers describe their work on disease.

At the Koch Institute for Integrative Cancer Research, scientists and engineers are collaborating on speeding up the time between a discovery in the lab and the delivery of treatments to patients. According to Koch Associate Director Jacqueline Lees, nearly 30 years elapsed from identifying oncogenes to an effective cancer treatment. One project underway is Michael Cima’s development of a microchip that can be implanted when a tumor is removed; the device reports any re-growth of the tumor, which can be quickly treated. His newest research with Professor Robert Langer successfully used the microchip to deliver medication.

Few effective treatments exist for the serious mental health diseases that are estimated to cost, in the US alone, some $317 billion per year in treatment and lost productivity. Despite that, Robert Desimone, director of the McGovern Institute for Brain Research, feels this is a revolutionary time for potential new treatments because of advances in genomics, neuroscience systems, and neuroimaging. He pointed to the work by Guoping Feng on the role of synapses in brain disorders—discovered through new neuron-imaging techniques.

Just as MIT coined the term, “neuroscience” in the 1960s, a new group of researchers has coined the “social brain,” says Mirganka Sur, director of the Simons Center for the Social Brain that studies how social cognition is wired into human beings. Focusing on autism, now diagnosed in one of 88 US children, Sur says the group is working to “understand the neural mechanisms underlying social cognition and behavior and understand what goes wrong.” One new approach using new imaging techniques is embodied in Rebecca Saxe’s new work on locating the specific brain area activated when children try to understand what others think.

Learn more at the MIT School of Science website.

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The EmTech Conference, MIT Technology Review’s annual gathering of researchers and leaders in emerging technologies, took place on Oct. 24-26, 2012. The conference focused on innovative ideas with potential for commercial impact, including new methods of alternative energy, technology-influenced education, and social media’s impact on data analysis.

Held at the Media Lab, the conference had a heavy Institute influence, with presentations from close to a dozen alumni, faculty, and affiliated researchers.

David Keith PhD ’91, professor of applied physics and professor of public policy at Harvard University, argued for adding one million tons of sulfuric acid to Earth’s upper atmosphere, which could shade the planet from increased global warming. Keith believes geoengineering—interventions in Earth’s climate to prevent rising temperatures—will a feasible option within the next 50 years, but political problems will arise. [Watch “Reigniting Innovation.”]

“Once you invent a new technology, you have no idea where it will go… (Geoengineering) could lead to two nuclear-armed states fighting over the thermostat.”

Andrew Fiore SM ’04

Facebook data scientist Andrew Fiore SM ’04 discussed social media’s reshaping of society, Facebook’s always-evolving news feed, and what influences Facebook users. Fiore says, in today’s society, there is minimal difference between online and offline behavior. [Watch "The Personal Implications of Big Data."]

“Online behavior is quickly becoming the behavior of humanity…Strong relationships are individually more influential, but weaker ones are collectively more influential.”

Idit Harel Caperton PhD ’88, president of the World Wide Workshop, and Nicholas Negroponte ’66, MArch ’66, founder of One Laptop Per Child, discussed technological approaches to teaching and learning. [Watch "Education and Learning."]

Negroponte described a field experiment that delivered one solar-powered tablet—filled with games, books, cartoons, and movies—to each child in two remote Ethiopian villages, without instruction. Within five minutes, the tablets were unboxed. After the first week, each child averaged 47 apps per day. After week two, the children were singing the alphabet.

“The big question is: will they learn to read? If they can, it can impact the 100 million kids who don’t go school, and impact the kids who go to school but don’t learn to read.”

Idit Harel Caperton PhD ’88

Capterton advocated for Media Lab-like thinking in public schools, including learning-by-design, and using gaming to alter student attitudes towards school.

“Every child in this country should learn English, Spanish, Chinese—and coding…When the only constant is change, we all need to become expert learners.”

The conference also honored this year’s TR35—Technology Review’s selection of the top 35 innovators under age 35. This year’s list includes Ken Endo PhD ’12, Abraham Flaxman ’00, Drew Houston ’05, Shishir Mehrotra ’00, and Baile Zhang PhD ’09, plus six MIT-related faculty, post-docs, and researchers.

View more information and videos—which includes presentations from Media Lab Director Joi Ito, edX President Anant Agarwal, and Ken Morse ’68—at EmTech 2012.

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The winning dish from the contest "Summer: a Short Story" (a dish based on an original poem, story, or song with a summer theme).

What happens when you get MIT students together for weekly roommate dinners? If you’re foodies like Mark Watabe SM ’10 and Tiffany Chu ’10, the casual affairs turned into opportunities for spirited competition with fellow MIT students one-upping each other in pursuit of delighting friends’ palates.

So fond were these memories that Watabe and Chu decided to take the idea public. Earlier this year, the duo launched Social Colander, a supper club cooking contest. Here’s how it works. Each month, three pairs of amateur chefs prepare a dish based on a theme. Previous themes have included “I Love Your Tasty Puns” (edible puns), “Tea-ny Delights” (food miniatures paired with tea), “Interracial Marriage” (a fusion of different ethnic flavors), and “When a Twinkie Dreams” (a gourmet re-envisioning of cheap, industrial fast food).

Some 20 guests enjoy the food and vote on their favorite dish. Think Iron Chef or Top Chef minus the commercials. And unlike the TV contests, the cheftestants are given ample time—weeks—to plan. “We want our chefs to come super prepared and bring their best game,” Watabe told online news site BostInno.

The winning chefs claim a gift certificate to a local restaurant and a chance to wear the prized trophy: a green colander hat.

Tickets aren’t easy to come by, and you have to sign up for the email list to be considered. The monthly club is currently based in Cambridge, though Watabe and Chu are hoping to expand to other cities nationwide and are currently shooting a Kickstarter video in preparation for fundraising.  The next dinner will be held Oct. 20 with the theme “Heaven & Hell,” which requires the chefs to combine spicy and soothing flavors. View the menu.

Watabe and Chu both studied architecture at MIT and work as designers by day. Chu is also an avid blogger and photographer and regularly contributes to online design publications such as Dwell and Core77.

Cheftestants from the "Summer: a Short Story" dinner. One member of the winning team, center, sports the prized green colander. Social Colander creators Mark Watabe SM '10 and Tiffany Chu '10 are in front.

Cheftestants from the “Summer: a Short Story” dinner, which required dishes based on an original poem, story, or song with a summer theme. One member of the winning team, center, sports the prized green colander. Social Colander creators Mark Watabe SM ’10 and Tiffany Chu ’10 are in front. Above: the dinner’s winning dish, called I Scream You Scream. It includes three savory scoops served in a waffle cone with all the tasty toppings: Swedish meatball with lingonberry sauce atop polenta, homemade pickles sprinkled with dill, and rainbow beets sprinkled with lemon zest.

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